Bukayo Saka suffered an injury to his right leg during England’s 2-1 defeat to Greece at Wembley Stadium on Thursday.
The Arsenal forward was forced to leave the match in the 51st minute, replaced by Chelsea winger Noni Madueke.
Saka was seen stretching and holding his right leg before eventually sitting on the turf after Greece took the lead.
England’s interim head coach, Lee Carsley, confirmed that Saka is being assessed for the extent of the injury.
While England were already missing injured duo Harry Kane and Jack Grealish, both are expected to be fit for their upcoming match against Finland on Sunday.
Arsenal, meanwhile, are without captain Martin Odegaard, who suffered an ankle injury while playing for Norway in September.
The Gunners return to Premier League action on October 19th against Bournemouth at Vitality Stadium.